Research Studies
If you are having psychotic-like experiences, such as unusual thoughts, odd beliefs, suspiciousness, or hallucinations, you may be a good fit for the following studies:
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Telehealth Adaptation of Group and Family-Based Cognitive Behavioral Therapy: This study offers 15 weeks of cognitive behavioral therapy (CBT) to youth ages 14-25 at clinical high risk and their families. The CBT sessions are conducted twice weekly, with the first session of the week being a skill-learning session that follows a workbook and the second session of the week being an individual therapy session where youth can personalize the CBT skills they are learning to their own lives in order to feel better and achieve their goals. Participants are randomly assigned to one of three types of therapy for the skill learning sessions: individual therapy, family therapy, or group therapy (which includes a parallel group for the family members). All study assessments and therapy sessions are conducted via telehealth. All evaluations are free of charge and participants are reimbursed for the time it takes to complete study assessments.
ProCAN Study (Psychosis Risk Outcomes Compound Assessment Network): This is a clinical trial at 15 institutions across the United States, including the Icahn School of Medicine at Mount Sinai. The aim of this study is to monitor changes in individuals who may be at Clinical High Risk (CHR) for psychosis after 8 weeks of taking the study drug, MT1988, which is aimed to improve cognition and thinking. -
Computational Phenotyping of Face Expression in Early Psychosis (FACES) Study: The purpose of this study is to describe patterns in face expression and language in individuals who have psychotic-like experiences. We are currently recruiting individuals between the ages of 15 and 40 who are at-risk for psychosis or have an onset of psychosis in the past 10 years. This study is entirely remote and involves clinical assessments, cognitive testing, and a recorded open-ended interview over Zoom.
Psychiatric Biomarkers Network (PBN) Study: This research study is looking for people between the ages of 18 and 50 who have schizophrenia-like experiences, people with a diagnosis of Bipolar l disorder, and healthy comparison individuals. The purpose of this study is to identify objective biological markers for schizophrenia and bipolar disease progression and treatment efficacy. Participants in this study will complete questionnaires about their life experiences and medical history, and undergo neurological assessment, brain imaging, a brief physical exam, collection of blood, urine, and cerebrospinal fluid (CSF) via lumbar puncture, also known as a spinal tap.
Reward, Salience, and Value Processing in At-Risk Youth (RSVP) Study: The purpose of this study is to use tasks and brain imaging to understand how people learn and make decisions, especially about what may be rewarding or important to them. This study includes both people who have unusual experiences and those who don’t. The knowledge gained from this study can be used to develop better treatments for young people with unusual experiences who may have difficulty with enjoyment and motivation.